ASPET on X: "This commentary refutes a recent claim that Kirchhoff's laws of electrical network can be applied to organ clearance models, including the widely used well-stirred model of hepatic elimination. Concerns
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Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data - ScienceDirect
第103回薬剤師国家試験 問172（理論問題） 、well−stirred model - yakugaku lab
Assessing Liver-to-Plasma Partition Coefficients and In Silico Calculation Methods: When Does the Hepatic Model Matter in PBPK?,Drug Metabolism and Disposition - X-MOL
Assessment of the Kochak-Benet Equation for Hepatic Clearance for the Parallel-Tube Model: Relevance of Classic Clearance Concepts in PK and PBPK | The AAPS Journal
SOLVED: Consider the well-stirred tank shown in the figure below. In this process, constant and equal inlet and outlet volumetric flows, liquid densities, and heat capacities are assumed; all of these properties
Impact of ignoring extraction ratio when predicting drug-drug interactions, fraction metabolized, and intestinal first-pass contribution. - Abstract - Europe PMC
Solved 6.6 Inthe well-stirred-reactor literature, a"reactor | Chegg.com
There is Only One Valid Definition of Clearance: Critical Examination of Clearance Concepts Reveals the Potential for Errors in Clinical Drug Dosing Decisions | The AAPS Journal
Five representative liver models: (a) the well-stirred or venous... | Download Scientific Diagram
Well‐stirred models for hepatic clearance. Equations show how the... | Download Scientific Diagram
Exploring the Pharmacokinetic Mysteries of the Liver: Application of Series Compartment Models of Hepatic Elimination,Drug Metabolism and Disposition - X-MOL
Continuous stirred-tank reactor - Wikipedia
Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data - ScienceDirect
Discussions on the hepatic well‐stirred model: Re‐derivation from the dispersion model and re‐analysis of the lidocaine data | Semantic Scholar
薬剤師国家試験 第107回 問176 過去問解説 - e-REC | わかりやすい解説動画！
Comparison of the well-stirred models. | Download Table
Hepatic clearance concepts and misconceptions: Why the well-stirred model is still used even though it is not physiologic reality? - ScienceDirect
The impact of using the well-stirred liver model in PBPK modelling for high-clearance compounds
Hepatic clearance concepts and misconceptions: Why the well-stirred model is still used even though it is not physiologic reality? - ScienceDirect
Ideal Stirred Tank Reactor System
Discussions on the hepatic well‐stirred model: Re‐derivation from the dispersion model and re‐analysis of the lidocaine data | Semantic Scholar
Examination of the Utility of the High Throughput In Vitro Metabolic Stability Assay to Estimate In Vivo Clearance in the Mouse ~ Fulltext
Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data - ScienceDirect
Intrinsic Clearance Arthur G. Roberts. Hydrophobic vs. Hydrophilic more bound to plasma proteins more distributed throughout body more metabolized. - ppt download
